What is preparative chromatography? Today, I will take you to understand what preparative chromatography is. Preparative chromatography refers to the use of chromatographic technology to prepare pure substances, that is, to separate and collect one or more chromatographically pure substances. The concept of "preparation" in preparative chromatography refers to obtaining sufficient quantities of a single compound to satisfy research and other uses. The emergence of preparative chromatography established a link between chromatography technology and economic interests. Preparation volume and cost are two important indicators of preparative chromatography. Among them, gas chromatography preparative chromatography is mainly used for the preparation of chromatographically pure samples of petrochemical products and volatile natural products. Introduction: Many friends who are new to the field of chromatography are unfamiliar with the term preparative chromatography. In fact, chromatography an

Chromatographic techniques that use supercritical fluids as the active phase are called supercritical fluid chromatography. Although supercritical fluid chromatography appeared in the 1960s, it was not successfully used until the 21st century. At present, supercritical fluid chromatography is still a relatively new chromatographic analysis method, and many people do not know much about it. Here is a brief introduction to its characteristics and scope of application. Comparison of supercritical fluid chromatography with gas chromatography and high performance liquid chromatography. SFC supercritical fluid chromatography columns are mainly used to analyze a variety of soluble compounds; the separation principle is that CO2 is used as the mobile phase by changing the chromatographic column, pressure and temperature. , add organic cosolvents to regulate separation; no derivatization is required when analyzing volatile compounds. Gas chromatography is mainly used to analyze volatile and ref

DAC dynamic axial compression columns adopt DAC dynamic axial compression technology to prevent bed collapse or eliminate the impact of bed collapse. Conventional axial compression technology is difficult to fill a chromatographic column with high column efficiency, so only dynamic axial compression technology can be used. DAC is recognized as the only technology that can maintain good separation effects in column chromatography of all sizes. It is also the most popular column packing technology in the field of preparative chromatography today. The advanced DAC dynamic axial compression preparatory column system can pack and maintain columns by itself. pressure, self-unloading, and has the functions of both a chromatographic column and a column packing machine

Liquid chromatography is a type of instrument that uses the difference in the distribution ratio of the mixture between the stationary phase and the mobile phase to separate and analyze the mixture. It can be used to separately analyze high-boiling point, thermally unstable, and high-molecular compounds that account for nearly 80% of the total organic matter. Among them, high-performance liquid chromatography has the advantages of high speed, efficiency, high selectivity, and high sensitivity, and is now widely used in experiments. Laboratory, chemical engineering, biology, medicine, environment, food and other fields.

Regis liquid chromatography column: REGIS Technology Company has always been in an international position in the chiral separation of compounds. Its main product PIRKLE chiral stationary phase has the following advantages

Chromatography is a technique that separates a mixed sample into its individual components. Chromatographic techniques were originally used to separate and recover (separate and purify) the components of a sample. Today's sophisticated chromatographic techniques are commonly used to separate and quantify sample components.

The Chemistry Dictionary tells you what a chromatography column is and what it does. A chromatographic column is a tube packed with a stationary phase to separate mixed components. It consists of column tube, pressure cap, ferrule (sealing ring), sieve plate (filter disc), joints, screws, etc. So what is a chromatography column?

With the development of modern industry and the widespread application of industrial products, industrial chemicals have entered the environment in large quantities and are commonly found in soil, water, organisms, air and atmospheric dust, becoming ubiquitous pollutants in the environment. HPLC has been and will remain an important tool for the separation and analysis of environmental pollutants.

Since it is a gas at normal temperature and pressure, liquefied gas samples can be injected into the gas phase after vaporization or directly into the liquid phase. Early standards used the method of sample injection after vaporization. Generally, the cylinder was turned upside down, a section of stainless steel coil was connected to the bottom, soaked in a water bath, and the quantitative loop injection port was connected to the back. Theoretically, this is equivalent to gas phase injection.

Sample filtration is a key step in preparing samples for chromatographic analysis. If the sample is not filtered before the experiment, problems such as column frit clogging will occur, resulting in increased back pressure and reduced column performance. This will increase the time spent on troubleshooting and maintenance of the chromatograph, wasting time and increasing the workload of scientific researchers. For most types of samples, filtration processing is relatively simple. Use the solvent inlet filter to filter the mobile phase before injection. This step is also very important. The chromatography filter head can effectively filter out solid particle impurities in the mobile phase; unfiltered solvents or microorganisms growing in solvent bottles will reduce the performance of the liquid chromatography column and pump. After a period of use, the solvent inlet filter needs to be cleaned or replaced regularly. When analyzing the food and beverage industry, some thick syrups, fruit

Principle Gas Chromatograph uses gas as the mobile phase (carrier gas). When the sample is "injected" into the injector by the microsyringe, it is carried by the carrier gas into the packed column or capillary chromatography column. Due to the difference in distribution or adsorption coefficient of each component in the sample between the mobile phase (gas phase) and the stationary phase (liquid phase or solid phase) in the chromatographic column, under the flushing of the carrier gas, each component repeatedly moves between the two phases. Sub-distribution separates each component in the column, and then uses a detector connected after the column to detect each component in order according to the physical and chemical properties of the components [1]. The signal given by the detector for each component appears as peaks on the recorder, called chromatographic peaks. The maximum value on the chromatographic peak is the basis for qualitative analysis, and the area covered by the chromato

"Accuracy" is very important in chromatographic experimental analysis. In order to achieve ideal accuracy, we will use many instruments and equipment during the experiment. Among them, the equipment that can quantitatively send samples into the chromatographic column is called an injector. The chromatography sampling controller is an intelligent automatic sampler that can complete the automatic sampling process by setting the sampling parameters and placing the sample to be tested. Dynamic compensation technology and modern touch screen dynamic display technology effectively improve the performance and quality of the instrument. The unique gas replacement mode makes MS operation safer and more reliable and extends the service life of the filament. This is how it works: 1. The PC sends instructions and parameters to the controller, and the controller generates corresponding signals to control the rotation of the sample tray motor to complete the positioning of the sample label number; 2

Preparative chromatography is a chromatographic system with the purpose of separating pure substances. Analytical chromatography is a chromatography system with the purpose of analyzing sample component information. Based on their different purposes, preparative chromatography has many different characteristics than analytical chromatography.

As more and more customers choose us as a supplier of column packing services, our services will play an increasingly important role in the separation and purification of customers. Zhansa Shanghai Laboratory further improves the quality and stability of services, and at the same time provides traceable loading services to customers who have close cooperation. In the future, every time a customer will install a column, a corresponding file will be established in the company, which can be accessed and analyzed at any time.

Just after the Spring Festival of the Year of the Rat, the newly renovated customer service laboratory was put into operation. Compared to before, the new laboratory is located in the Xinzhuang Hub with more convenient transportation. In order to better serve our customers, the new laboratory covers an area of 4 times larger than before, strictly distinguishes various functional areas, and runs more standardized and rigorous. At the same time, the laboratory has also passed a formal environmental assessment to ensure that customers can receive lasting and formal services.

The use of 150mm and 200mm inner diameter high-pressure preparation columns is becoming more and more widespread, but the only solution currently on the market is the dynamic axial compression system, referred to as the DAC system.

Zhansa officially launched a new type of long-life protection column. The protection column adopts an epoch-making adaptive structure, which can effectively compensate for the slight collapse of the column head during the use of the protection column. Its very simple and fast packing also adopts the wet method instead of the traditional dry packing of other guard columns, which can effectively protect the preparation column and reduce the frequency of packing.

Safety is always our most important commitment to customers. As accessories or equipment used under high pressure for a long time, passing the world's highest level of safety certification is our guarantee for customers.

After 3 years of development and testing, Zhesa officially launched a full range of self-adaptive preparation columns to help the separation and purification of high-efficiency pharmaceutical active ingredients. Our development team includes engineers from the aviation industry with many years of manufacturing and design experience, as well as scientists from the front line of preparative separation and purification with more than 20 years of chromatographic separation experience. We strive to make products that need to be refined and polished to perfectly match the needs and take into account cost advantages!